Anticancer Activity of Cissus Quadrangularis
S Geetha1, R Vasuki2
1S Geetha, Research Scholar, Department of Biomedical Engineering, Bharath Institute of Higher Education and Research, Selaiyur, Chennai, India.
2R Vasuki, Professor and Head, Department of Biomedical Engineering, Bharath Institute of Higher Education and Research, Selaiyur, Chennai, India.
Manuscript received on 17 April 2019 | Revised Manuscript received on 24 April 2019 | Manuscript published on 30 April 2019 | PP: 603-605 | Volume-8 Issue-6, April 2019 | Retrieval Number: F3793048619/19©BEIESP
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© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: Validation of the useful medicinal properties of various indigenous plants has gained immense importance as they can be used as an alternative source of lead compounds in pharmacological industries to tackle many modern day problems such as drug resistance in microorganisms and non-specificity in chemotherapeutic agents. Cissus quadrangularis Linn. is one such plant which has been widely used for medical purposes in traditional systems of medicine. Hence this work seeks to validate the anticancer property of methanolic and ethanolic extracts of the plant against HeLa cell line. The IC50 concentration was recorded at 62.5 ug/ml for methanolic extract and 125ug/ml for ethanolic extract. The results clearly revealed that the methanolic extract of Cissus quadrangularis was more potent on HeLa cell line when compared to ethanolic extract.
Keyword: HeLa Cell line, Ethanol Extract, Methanol Extract.
Scope of the Article: Biomedical Computing