Innovative Technology for Modeling Cancer Grow Regulatory Mechanisms with Taking into Account Micro-RNA Action
Mahruy Saidalieva1, Mohiniso Bahromovna Hidirova2
1Mahruy Saidalieva, Scientific and Innovation Center of Information and Communication Technologies, Tashkent University of Information Technologies named after Muhammad Al-Khwarizmi, Tashkent, Uzbekistan.
2Mohiniso Baxromovna Hidirova*, Scientific and Innovation Center of Information and Communication Technologies, Tashkent University of Information Technologies named after Muhammad Al-Khwarizmi, Tashkent, Uzbekistan.
Manuscript received on October 14, 2019. | Revised Manuscript received on 24 October, 2019. | Manuscript published on November 10, 2019. | PP: 1705-1709 | Volume-9 Issue-1, November 2019. | Retrieval Number: A5174119119/2019©BEIESP | DOI: 10.35940/ijitee.A5174.119119
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© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: This article is devoted to modeling regulatory mechanisms of human molecular-genetic systems activity during cancer origin and development with taking into account non-coding circulating regulators. The paper draws on results made by using methods of quantitative and qualitative analysis of functional-differential equations. Computational experiments have shown that for certain values of internal and external states there are the following regimes: programmed cell death (apoptosis), stationary state, self-oscillations, irregular behavior (cancerous growths) and a sharp destructive change – the “black hole” effect (metastasis) in depending on various concentrations of micro-RNA. The paper provides a new mathematical and computer models able to describe regulatory mechanisms of cancer taking into account spatial and temporal relations.
Keywords: Mathematical Modeling, Functional-Differential Equations, Chaos, Nonlinear Systems, Qualitative Analysis, Living Systems, Cancer, Micro-RNA.
Scope of the Article: Bio-Science and Bio-Technology