Translation Enhancement of m-Rna by Immuno Evasion Proteins
Narmata Arya
Narmata Arya, Department of Biotechnology, Sanskriti University, (Uttar Pradesh), India.
Manuscript received on 05 October 2019 | Revised Manuscript received on 19 October 2019 | Manuscript Published on 26 December 2019 | PP: 235-237 | Volume-8 Issue-12S October 2019 | Retrieval Number: L106510812S19/2019©BEIESP | DOI: 10.35940/ijitee.L1065.10812S19
Open Access | Editorial and Publishing Policies | Cite | Mendeley | Indexing and Abstracting
© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open-access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: In this paper, mono-functional EKB i.e. “E3”, “K3” and “B18R” derived from vaccinia virus is compared with multi-functional NS1 derived from “influenza A virus” to compare their ability for the enhancement of the mRNA translation. Further, expression of luciferase was transferred by delivery of unmodified luciferase assorted with NS1 mRNA and compared with delivery of unmodified luciferase assorted with either “E3”, “K3” or “B18R” respectively. Various combination of “E3”, “K3”, “B18R” were assorted with NS1-TX91 mRNA at different ratios and delivered with m RNA of luciferace.
Keywords: Luciferase, NS1 (Non-Structural Protein 1), EKB, m-RNA, Translation.
Scope of the Article: Bio-Science and Bio-Technology